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# Bioengineering

BIOE 332: THERMODYNAMICS

Trinity College Dublin

3B1: Thermodynamics

This course has been developed to strengthen the student’s skills in the thermal fluid sciences and is organised into three main subsections: heat transfer, thermodynamic cycles and high-speed flows. The heat transfer part deals primarily with conductive heat transfer and develops the mathematical modelling skills and analysis techniques for practical conductive heat transfer problems based on the fundamental scientific principle of conservation of energy. The thermodynamic cycles portion focuses on steam and gas power generation and refrigeration. The students’ understanding of basic thermodynamic processes, properties and principles is expanded upon by applying them to perfect (Carnot), ideal (reversible) and actual (irreversible) mechanical engineering devices. The high-speed flow section introduces to students to compressibility, the speed of sound, subsonic, trans-sonic and supersonic flow through nozzles.

Syllabus

BIOE 332: THERMODYNAMICS

Georgia Tech – Lorraine

ME 3322: Thermodynamics

Introduction to thermodynamics. Thermodynamic properties, energy and mass

conservation, entropy and the second law, and second law analysis. Thermodynamic

analysis of power, refrigeration, and heat pump systems; vapor cycles and gas cycles.

Syllabus

BIOE 332: THERMODYNAMICS

Nanyang Technological University

BG2142: Biological Thermodynamics

This course introduces fundamental thermodynamics and its applications in biological systems. Gas law and the laws of thermodynamics. Gibbs Free energy and thermodynamic relations. Biological applications of the Gibbs Free energy. Phase equilibria. Reaction Kinetics and mechanisms.

Syllabus

BIOE 332: THERMODYNAMICS

National University of Singapore

CN2121: Chemical Engineering Thermodynamics

Learning outcomes:

• Describe and apply the laws of thermodynamics
• Apply mass and energy balances for closed and open systems
• Estimate thermodynamic properties of pure and mixed fluids
• Apply fundamental concepts to the analysis of practical systems (power cycles, engines and refrigeration cycles)
• Explain and estimate phase equilibria for pure and multicomponent systems and chemical reaction equilibria

Syllabus

BIOE 332: THERMODYNAMICS

15503: Thermal Engineering

This is a basic course of thermodynamics and an introduction to heat transfer. The program is divided into a thermodynamic section, a heat transfer section and a last section oriented to apply the acquired knowledge and student work. Section I: First and second laws of thermodynamics. Application to turbines, valves, compressors, pumps and heat exchangers. Thermal efficiency. Power cycles and refrigeration cycles. Section II: Introduction to heat transfer. Heat transfer principles: Fourier's law, Newton's law of cooling, Stephan-Boltzmann law. One-dimensional, steady-state conduction. Heat transfer from extended surfaces: fins design and performance. Transient conduction. Section III: Applications and student work.

Syllabus

BIOE 332: THERMODYNAMICS

15335: Thermal Engineering

To provide students with well-founded knowledge of several thermodynamic processes in engineering. To present from a critical perspective the principal assumptions and simplifications that lead to preliminary analyses and designs in thermal engineering. To capacitate students with skills in evaluating heat transfer by conduction, convection and radiation, and to use all these abilities in the design of heat transfer equipment. To be capable of characterising propulsive forces and how well the power produced by an engine is utilized in propelling an aerospace vehicle. To be able to discriminate the principal parameters controlling gas turbine and internal combustion engines, and their integration in aerospace propulsion systems.

Syllabus

BIOE 332: THERMODYNAMICS

University of Waikato

ENGME221: Engineering Thermodynamics

This paper covers the fundamental concepts and laws of thermodynamics, including thermodynamics properties of substances, first and second law analysis, power cycles, refrigeration cycles and simple combustion analysis of engines.

Syllabus

BIOE 342: LABORATORY IN TISSUE CULTURE

15566: Cell Culture and Biotechnology for Tissue Engineering

Regenerative Medicine (RM) and Tissue Engineering are multidisciplinary fields that apply the principles of life science, engineering, and basic science to the development of viable substitutes which restore, maintain, or improve the function of human tissues. This course is designed to provide an advanced knowledge of tissue and organ regeneration and a practical point of view to tissue engineering, understanding the biotechnological tools to generate each component. Students will be required to learn and gain expertise from analysis of primary literature about the design of tissue functional units.

The student will acquire the ability to design biological tissues by using advanced techniques in bioengineering and biotechnology from the developmental point of view. The students will acquire the ability to understand the importance of stem cells and gene therapy in order to succeed in the generation of a tissue, even in pathological situations.

Syllabus

BIOE 372: BIOMECHANICS

Nanyang Technological University

BG2109: Biomechanics

Biomechanics at different length scales. Mechanics of biomolecules. Mechanics of biomembranes and cells. Muscles and movement. Skeletal biomechanics. Terrestrial locomotion. Fracture fixation devices.

Syllabus

BIOE 372: BIOMECHANICS

National University of Singapore

BN2204: Fundamentals of Biomechanics

The module aims to introduce students to the applications of engineering statics and dynamics to perform simple force analysis of the musculoskeletal system; give an appreciation of kinematics and kinetics of human motions; apply the fundamentals of mechanics, i.e. stress and strain in biological systems, shear force, bending moment and torsion.

Syllabus

BIOE 391: NUMERICAL METHODS

Nanyang Technological University

BG2111: Computational Methods

Linear and non-linear algebraic equations. Least-squares regression and interpolation. Numerical differentiation and integration. Numerical solutions of ordinary differential equations (ODE).

Syllabus

BIOE 391: NUMERICAL METHODS

15543: Numerical Methods in Biomedicine

Using NUMERICAL METHODS -NM- to calculate approximate solutions of models of physiological, cellular, and molecular systems. Study the stability and accuracy of NM. Calculate numerical solution of systems of nonlinear equations. Approximate the minimum of a function of several variables. Developing, analyzing, and implementing finite difference methods. Solving ordinary differential equations and systems by numerical integration methods. Using the software environments to discuss the efficiency, pros and cons of different NM.

Syllabus

BIOE 3XX: DEPT APPROVED TRANSFER CREDIT

Trinity College Dublin

3BIO2 : Biomedical Design Project

This module aims to develop design skills according to a Conceive-Design-Implement-Operate (CDIO)

compliant methodology. It provides the students with theory, methods and practise to create insights

necessary to develop safe, effective and efficient medical devices, which are optimised for specific

functional requirements. The theory of different design approaches, relevant to medical device design is reviewed and discussed. Focussing on the CDIO design methodology, students will define the product/technology need and develop the design concept. The student will then focus on creating the design, i.e., the plans, drawings and 3D model which will define what will be implemented. The design will then be transformed into a product prototype using 3D printing or other suitable 3D modelling capability. In the final stage, Operate, the product will be analytically evaluated and mechanically tested to determine if it has met its design objectives. In the module, students will be provided with the necessary theory and practise to understand and follow the CDIO design process. Students will learn the use of 3D CAD (Solidworks) and use the software to design their prototype product. The students will be presented with a range of suitable methods for evaluation and testing, which can be utilized at different stages of the design process to review and test medical design concepts and prototypes. The module will provide students with an introduction to multidisciplinary project teams and the opportunity to apply learned knowledge to a real-world problem within group project work. The module structure is based on project-based learning. Each week students are introduced to new content, which they learn to apply by engaging in activities, practical implementation and discussion. The design project is based on a real-world problem.

Syllabus

BIOE 420: BIOSYSTEMS TRANSPORT PHENOMENA

The University of Melbourne

BMEN 30007: Biotransport Processes

This subject introduces transport processes in biomedical systems, complementing and reinforcing material learned in related biology subjects. Students will be introduced to the process of developing engineering models and simple conceptual designs in the context of biological systems. The subject covers fundamental concepts of diffusion and conservation within momentum, heat and mass transport. Within momentum transport, specific topics include Newton’s law of viscosity, viscosity of gases and liquids, conservation of momentum, velocity distributions in simple laminar flows, boundary layer concepts and turbulence and the Reynolds number. Within heat transport, Fourier’s law of conduction is covered. Within mass transport, specific topics include Fick’s first and second laws of diffusion, diffusivities of gases, liquids and solids, binary mixture diffusion and conservation of mass, concentration distributions in simple binary systems including identifying appropriate boundary conditions, concentration boundary layer concepts, Schmidt and Sherwood numbers, definition and use of mass transfer coefficients. Students will examine transport of molecules and cells in biological systems to describe various key processes, such as cell migration and provision of cell nutrition. The role of transport processes in biological systems and employed in clinical applications, such as dialysis, will be described using simple engineering models.

Syllabus

BIOE 490: INTRO SYSTEMS BIOLOGY MODELING

Indian Institute of Technology Bombay

CL 663: Introduction to Systems Biology

Complexity in biological systems; Basic concepts of biological networks; Genetic networks, Transcription networks, Protein networks; Network motifs; Deterministic modeling approaches – kinetics, dynamics; Dynamics of and multiplicity in biological systems – bistability, oscillations, synchronization; Introduction to probability; Stochastic modeling approaches – Introduction, Langevin technique, Master equations, quasi-steady state approximation; Numerical simulations – Gillespie algorithm, Monte Carlo simulations; Fluctuations and robustness; Pattern formation; Traveling waves in biological systems; Quantitative experimentation.

Course Description

BIOE 548: NEURAL SIGNAL PROCESSING

The University of Melbourne

BMEN90002: Neural Information Processing

This subject introduces students to the basic mechanisms of information processing in the brain and nervous system, as well as both neural prostheses (that interface the neural system with therapeutic electrical devices) and artificial systems based upon the principles of neural processing (neuromorphic engineering). Topics covered include: neural properties underlying information processing in neurons, generation and propagation of action potentials (spikes), Hodgkin-Huxley equations, coding and transmission of neural information, simplified neural models, synaptic plasticity and learning in biological neural systems, learning in artificial neural systems, measurement of biological neuralsignals, neural prostheses, neuromorphic engineering.

Syllabus

BIOE 574: CONTINUUM BIOMECHANICS

Indian Institute of Technology Kanpur

ME621A: Introduction to Solid Mechanics

Mathematical Preliminaries: Vector and tensors calculus, Indicial notation. Strain: Definition of small strain, Strain-Displacement relations in 3D, Physical interpretation of strain components, Principal Strains. Stress and equilibrium: Stress components in 3D, Principal Stresses, Cauchy’s principle, stress equilibrium. Constitutive law, Navier’s equations, compatibility equations. Formulation of boundary value problems and solution methods: Plane Problems – plane stress, plane strain, anti-plane shear. Fourier transform methods. Superposition principle. Additional topics from: Examples - Torsion of prismatic shaft, Contact problems, Wedge problems, Dislocations and inclusions, Cracks, Think-film problems; Advanced transform methods - Complex variable techniques, Potential methods; Advanced ideas - Energy method, Numerical approaches, Finite elements, Eigenstrains, Micromechanics.

Syllabus

BIOE 574: CONTINUUM BIOMECHANICS